MLB DFS Sleeper Fantasy Picks for Today (Wednesday, April 22nd)

I’m here to share a few of my top plays for today’s MLB slate on Sleeper Fantasy, with most of these picks based on our most recent projections.

Remember, these are among our highest-rated selections at the time of writing, but MLB news is always evolving and could affect the value of these plays. Our MLB DFS projections team is constantly updating their numbers to stay current.

Below, I’ll break down my approach for Sleeper Fantasy on this Wednesday slate.

Sleeper
Get Free $20+100% Deposit Match up to $100!
Must be 18+ (19+ or 21+ depending on state of residence) and within applicable state. Not available in NJ. Full T&Cs apply.
LABSBONUS
Promo Code

First… Sign Up to Make MLB Sleeper Fantasy Picks

If you’re ready to join the action but haven’t signed up yet, you can claim a special offer with our Sleeper Fantasy promo code to unlock a generous bonus. Sleeper Fantasy is one of the most recognized and widely popular DFS pick’em sites. Every day, they release player projections for MLB games. It’s up to us to predict whether a player will exceed or fall short of those projected stats in their matchup. With a wide range of players to choose from, you just need to make a minimum of two selections to enter.

I’ll be using our projections that are integrated into PickLabs to find meaningful edges on how players might fare in different stat categories. When making your MLB Sleeper Fantasy picks today, be sure to check out PickLabs for all of the top player prop and DFS pick’em edges.

Sleeper Fantasy MLB Picks for Wednesday

Now that you’re signed up, here are some of our top MLB picks on Sleeper Fantasy for Wednesday:

  • Zack Littell less than 3.5 Pitcher Strikeouts
  • Eduardo Rodriguez less than 4.5 Pitcher Strikeouts
  • Brice Turang more than 1.5 Hits + Runs + RBIs

Braves vs. Nationals MLB Sleeper Fantasy Picks

Zack Littell less than 3.5 Pitcher Strikeouts

The pitcher strikeouts projection for Zack Littell looks like a strong pick based on the current data. The Sleeper projection of 3.5 compares favorably based on our MLB simulations. This pick projects to hit 68.1% of the time based on the assumptions, and that represents a 7.8% edge.

White Sox vs. Diamondbacks MLB Sleeper Fantasy Predictions

Eduardo Rodriguez less than 4.5 Pitcher Strikeouts

The pitcher strikeouts projection for Eduardo Rodriguez looks like a strong pick based on the current data. The Sleeper projection of 4.5 compares favorably based on our MLB simulations. This pick projects to hit 63.3% of the time based on the assumptions, and that represents a 7.5% edge.

Brewers vs. Tigers MLB Sleeper Fantasy Predictions

Brice Turang more than 1.5 Hits + Runs + RBIs

The hits + runs + RBIs projection for Brice Turang looks like a strong pick based on the current data. The Sleeper projection of 1.5 compares favorably based on our MLB simulations. This pick projects to hit 62.6% of the time based on the assumptions, and that represents a 6.4% edge.

Pictured: Zack Littell

Photo Credit: Imagn

About the Author

Justin Bailey is the Lead Editor for RotoGrinders and FantasyLabs. He’s been playing DFS since 2013 and specializes in small-field NFL and PGA contests. Justin qualified for the DraftKings Fantasy Golf World Championship in 2023.