I’m here to share a few of my top picks for today’s MLB slate on PrizePicks. Most of these predictions are heavily based on our projections.
Be mindful of the fact that these are what we deem to be optimal picks at the time of publish. Just like with any sport, the news cycle in the MLB is fluid, so the picks below may become more or less appealing depending on a variety of factors. But rest assured that our MLB DFS projections team is constantly making updates.
Below, I’ll detail how I’m approaching things on PrizePicks for Wednesday.
First… Sign Up to Make MLB PrizePicks Picks
If you’re interested in joining the action but haven’t signed up yet, you can claim a special offer with our PrizePicks promo code “LABS” to get $50 on a $5 entry! PrizePicks is one of the most popular DFS pick’em sites. They provide player projections for MLB matchups each day. From there, it’s up to us to determine whether a player will surpass or be lower than those projections in their games. With a wide selection of players to choose from, you only need to make at least two picks to create an entry.
I’ll be using our FantasyLabs projections to find meaningful edges on how MLB players might fare in different stat categories. For additional insight as you make your PrizePicks picks today, check out our fantasy pick’em tool, where you’ll find all of our picks for a variety of pick’em sites.
PrizePicks MLB Picks for Wednesday
Now that you’re signed up, here are some of our top MLB picks on PrizePicks for Wednesday at a glance:
- Jeremy Pena (HOU) Less Than 7.5 Fantasy Score
- Jarren Duran (BOS) Less Than 8.5 Fantasy Score
- MacKenzie Gore (WAS) Less Than 34.5 Fantasy Score
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Cubs vs. Nationals MLB PrizePicks Predictions
MacKenzie Gore less than 34.5 Fantasy Score
The Fantasy Score projection for MacKenzie Gore looks like a strong pick based on the current data. The PrizePicks projection of 34.5 compares favorably based on our MLB simulations. This pick projects to hit 61.3% of the time based on the assumptions, and that represents a 7.0% edge.

Astros vs. Pirates MLB PrizePicks Predictions
Jeremy Pena less than 7.5 Fantasy Score
The fantasy score projection for Jeremy Pena looks like a strong pick based on the current data. The PrizePicks projection of 7.5 compares favorably based on our MLB simulations. This pick projects to hit 57.8% of the time based on the assumptions, and that represents a 3.4% edge.
Angels vs. Red Sox MLB PrizePicks Predictions
Jarren Duran less than 8.5 Fantasy Score
The fantasy score projection for Jarren Duran looks like a strong pick based on the current data. The PrizePicks projection of 8.5 compares favorably based on our MLB simulations. This pick projects to hit 56.7% of the time based on the assumptions, and that represents a 2.3% edge.
Pictured: Jarren Duran
Photo Credit: Getty Images